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Update on Drugs and Drug News - Number 2 1999


Class Name/Company Approval Dates and Comments

Antiandrogen

Cyproterone 2 mg & ethinyl estradiol 35 mcg Diane-35®
Berlex Canada

Approved in Canada September 19, 1997 for the treatment of acne.

Antifungal

Oxiconazole nitrate 1% cream
Oxistat®
Glaxo Wellcome

Approved by the FDA August 18, 1997 for the treatment of tinea (pityriasis) versicolor. Directions for pediatric use have also been added to its labeling.

Terbinafine solution 1%
Lamasil®
Novartis

Approved by the FDA October 17, 1997 for the topical treatment of tinea (pityriasis) versicolor due to Malassezia furfur (formerly Pityrosporum ovale), and tinea pedis (athlete’s foot), tinea cruris (jock itch), or tinea corporis (ringworm), due to Trichophyton rubrum, Trichophyton mentagrophytes, or Epidermophyton floccosum.

Itraconazole
Sporanox®
Janssen Ortho

New, shorter dosage regimen approved in Canada August 8, 1997 for the treatment of tinea corporis/tinea cruris (200 mg daily for seven consecutive days) and tinea pedis (200 mg twice daily for seven consecutive days).

Antirosacea

Metronidazole cream
Noritate®
Dermik

Approved by the FDA September 26, 1997 for the topical treatment of inflammatory lesions and erythema of rosacea.

Antiviral

Famciclovir
Famvir®
SmithKline Beecham

Approved by the FDA September 17, 1997 for the suppression of recurrent episodes of genital herpes in immunocompetent adults.

Lamivudine and Zidovudine
Combivir®
Glaxo Wellcome

Approved by the FDA September 26, 1997 for the treatment of HIV infection.

Valacyclovir
Valtrex®
Glaxo Wellcome

Approved by the FDA September, 26 for the suppression of recurrent episodes of genital herpes in immunocompetent adults.

Corticosteroid

Hydrocortisone butyrate
Locoid®
Inveresk research

Approved by the FDA September 8, 1997 for the relief of inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.


In this issue:

  1. Imiquimod
  2. Antimicrobial Prophylaxis Prior to Dermatologic Surgery
  3. Update on Drugs and Drug News - Number 2 1998