Adapalene is a designer retinoid, with a similar molecular make-up with vitamin A. A guide to patient use, at what point in time should patients expect improvement, mechanism of action, side-effects, and other drug interactions are discussed in this article.
Combination therapy is a strategy of combining antibiotic treatments with other treatments with different mechanisms of action to treat acne. This has the effect of preventing or mitigating the unwanted effects of antibiotic resistant bacteria, and may confer other benefits such as lower required dosage as well.
Isotretinoin (Accutane®) is a retinoid or vitamin A analog, which means that its molecular structure is similar to Vitamin A. Mechanism of action, efficacy, side-effects, and contraindications are discussed as well as an FAQ section for this drug.
Isotretinion is a powerful drug, and sometimes the only treatment option for severe acne. The most common side-effects such as dry skin, dry eyes, and hair problems, and headaches, and other side-effects are discussed.
Isotretinion will require monitoring by a doctor. While relatively rare, side-effects can be serious, and affect blood, bone, liver, neurologic, and muscle, and require periodic testing to ensure safety and healthy. It is also teratogenic, so pregnancy will also be a part in patient education.
Oral contraceptives (OCs) have been available since 1960, and can be useful for treating certain types of acne. Various acne-approved OCs are discussed.
This article organizes contraceptive pills is to compare the effects that the progestins that are used will have on acne.
Progestin only and combination pills are discussed in this article. Monophasic, biphasic, and triphasic pills are considered and listed.
Oral contraceptives can have side-effects that are undesirable. Common and rare side-effects, contraindications, and possible drug interactions.
Progestins have multiple influences on acne. Cyproterone acetate, found in Diane-35® seems to be an exception in that it is not affected by estrogen.
LATEST: VOL 23-1, JAN 2018
Recent advances in the treatment of hereditary angioedema, particularly in the last decade has been promising. This paper reviews the mechanisms, efficacy, and adverse reactions associated with these new treatment medications.
An increasing body of research indicates that dietary change may serve as a component of therapy for certain skin conditions. This includes conditions such as acne, atopic dermatitis, aging skin, psoriasis, and rosacea. This article takes a high level overview of the role that diet may play in these conditions.
Update on drugs includes Onabotulinum-toxinA for injection (Botox® Cosmetic), Hyaluronic acid dermal filler (Restylane® Silk), Ustekinumab for SC injection (Stelara®), Golimumab for IV infusion (RSimponi Aria®), Herpes zoster vaccine (non-live recombinant, AS01B adjuvanted) suspension for IM injection (Shingrix), Brentuximab vedotin for IV infusion (Adcetris®)