Skin Therapy Letter HOME
Written for dermatologists by dermatologists. Indexed by the US National Library of Medicine.
Skin Information
Skin Therapy Letter About STL Subscribe Today SkinCareGuide Network Site Map

Derm News: 2007.22(10)

Generalized pruritus treated with narrowband UVB

International Journal of Dermatology, 46(4):367-370
Dilek Seckin, Zeynep Demircay, Ozlem Akin


Narrowband UVB phototherapy has been increasingly used in a variety of dermatological diseases. We planned to evaluate its efficacy in generalized pruritus in this prospective study.


Forty-six patients were included and then divided into two groups: group 1 and group 2 consisted of patients with uremic pruritus and "idiopathic pruritus", respectively. Phototherapy was given three times a week. Efficacy assessments were made by means of visual analog scale (VAS) and pruritus grading score.


Thirty-five patients completed the treatment. Mean VAS decreased from 8.2 1.5 to 3.6 3 in group 1 and from 7.1 2.3 to 2.3 2.8 in group 2 (P < 0.0001). Mean percentage of change in VAS was 54.2% (95% CI 32.6-75.9) and 67.9% (95% CI 53.8-81.9) in group 1 and group 2, respectively. Mean number of treatments was 22 in both groups. Mean cumulative UVB dose was 24,540 mJ/cm2 and 20,801 mJ/cm2 in group 1 and group 2, respectively.


Narrowband UVB is an effective and well-tolerated treatment option for patients with generalized pruritus.

    Back to Current Volume:   Dermatology News 2007.22

The Derm News service provided by the Editorial Consultants of Skin Therapy Letter© and its founding editor Dr. Stuart Maddin.