Dermatology News: 2007.23

• 2007.23(10) Phase II trial of subcutaneous injections of human recombinant interleukin-2 for the treatment of mycosis fungoides and Sézary syndrome
  We conducted a phase II trial to evaluate the efficacy and toxicity of subcutaneous injections of recombinant interleukin (IL)-2 in 22 heavily pretreated patients with advanced cutaneous T-cell lymphoma...   |   Read more ...



• 2007.23(9) Calciphylaxis: Natural history, risk factor analysis, and outcome
  Calciphylaxis is characterized by ischemic cutaneous ulceration, high mortality, and ineffective treatment...   |   Read more ...



• 2007.23(8) Basal cell carcinoma: treatment with imiquimod
  Basal cell carcinoma (BCC) is the most common cutaneous malignancy. There are various approaches to its treatment, but imiquimod, the immune response modifier, offers a topical...   |   Read more ...



• 2007.23(7) Azelaic acid (15% gel) in the treatment of acne rosacea
  In December of 2002, the FDA approved azelaic acid 15% gel for the topical treatment of inflammatory papules and pustules of mild to moderate rosacea...   |   Read more ...



• 2007.23(6) Pimecrolimus 1% cream in the treatment of vulvar lichen sclerosus in postmenopausal women
  Vulvar lichen sclerosus (LS), a poorly recognized chronic inflammatory skin disease, may represent a therapeutic challenge. Pimecrolimus cream 1% is a nonsteroidal, selective inflammatory cytokine inhibitor that has recently been indicated for some inflammatory cutaneous diseases...   |   Read more ...



• 2007.23(5) Annular atrophic lichen planus
  A 30-year-old woman presented with a 1-year history of a pruritic eruption on the extremities, characterized by several annular plaques. The patient had been treated unsuccessfully with medium-potency topical steroids...   |   Read more ...



• 2007.23(4) Apoptosis, P53 and Bcl-2 expression in response to topical calcipotriol therapy for psoriasis
  The histopathologic changes characteristic of psoriasis might be related to suppressed apoptosis. The P53 and Bcl-2 proteins play a central role in the regulation of apoptosis. This study aimed to evaluate P53 and Bcl-2 expression and apoptotic cells in the psoriatic skin before and after topical calcipotriol therapy...   |   Read more ...



• 2007.23(3) Nephrogenic fibrosing dermopathy/nephrogenic systemic fibrosis: a case series of nine patients and review of the literature
  Nephrogenic fibrosing dermopathy/nephrogenic systemic fibrosis (NFD/NSF) is a fibrosing cutaneous disorder recently recognized to have systemic manifestations...   |   Read more ...



• 2007.23(2) Topical zinc oxide vs. salicylic acid-lactic acid combination in the treatment of warts
  Warts are a common dermatologic problem. Treatment is painful, prolonged, and can cause scarring...   |   Read more ...



• 2007.23(1) A comparison of botanical and synthetic substances commonly used to prevent head lice (Pediculus humanus var. capitis) infestation
  Pediculosis, caused by head lice (Pediculidae: Pediculus humanus var. capitis), is experiencing a global resurgence, with the prevalence in primary schools averaging as high as 40% in some areas regardless of socioeconomic factors...   |   Read more ...

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The Derm News service provided by the Editorial Consultants of Skin Therapy Letter^© and its founding editor Dr. Stuart Maddin.