Dermatology News: 2007.8

• 2007.8(10) Photostability of commercial sunscreens upon sun exposure and irradiation by ultraviolet lamps
  Sunscreens are being widely used to reduce exposure to harmful ultraviolet (UV) radiation. The fact that some sunscreens are photounstable has been known for many years...   |   Read more ...



• 2007.8(9) In Vivo Stimulation of De Novo Collagen Production Caused by Cross-linked Hyaluronic Acid Dermal Filler Injections in Photodamaged Human Skin
  To determine whether endogenous synthesis of new extracellular matrix may contribute to the degree and duration of clinical benefits derived from cross-linked hyaluronic acid dermal filler injections...   |   Read more ...



• 2007.8(8) Blood concentrations of pimecrolimus in adult patients with atopic dermatitis following intermittent administration of pimecrolimus cream 1% (Elidel®) for up to 1 year
  Objectives: To determine blood concentrations of pimecrolimus after long-term intermittent administration of pimecrolimus cream 1% in adult patients with extensive atopic dermatitis (AD). Methods: This was an open-label, multiple topical dose study in adults with moderate to severe AD and a total body surface area (TBSA) involvement of at least 20%...   |   Read more ...



• 2007.8(7) Management of actinic keratosis patients: A qualitative study
  In order to reinforce the appropriate UV-related behaviour of patients with actinic keratosis (AK), it is of importance to understand the underlying psychological aspects of having AK. Materials and methods: Open and systematic explorative interviews were conducted with 15 AK patients...   |   Read more ...



• 2007.8(6) Alefacept in corticosteroid refractory graft versus host disease: Early Results indicate promising activity
  Steroid refractory graft versus host disease (GVHD) presents a significant therapeutic challenge due to the limited efficacy and safety of second-line treatments. Three patients with extensively pretreated, refractory GVHD were treated with a targeted anti-T-cell agent, alefacept, and demonstrated rapid and clinically significant improvement in their GVHD, facilitating tapering of corticosteroids...   |   Read more ...



• 2007.8(5) The impact of aggressive debridement used as an adjunct therapy with terbinafine on perceptions of patients undergoing treatment for toenail onychomycosis
  Objective: To determine whether adding aggressive debridement to oral terbinafine for treating toenail onychomycosis impacts patient-reported outcomes (PROs). Materials and methods: A total of 504 patients were randomized to receive 12 weeks of terbinafine 250 mg/day with or without debridement, with an additional 36-week follow-up...   |   Read more ...



• 2007.8(4) Skin care products and subtle data manipulation
  The dermatologists of today need to master the skills to help their patients in choosing skin care products. As physicians and scientists, we are naturally inclined to trust sophisticated and objectively derived data that are published in scientific...   |   Read more ...



• 2007.8(3) Cutaneous tuberculosis
  Cutaneous tuberculosis continues to be one of the most elusive and more difficult diagnoses to make for dermatologists practicing in developing countries. Not only because they have to consider a wider differential diagnosis (leishmaniasis, leprosy, actinomycosis, deep fungal infections, etc)..   |   Read more ...



• 2007.8(2) Two randomized studies demonstrate the efficacy and safety of dapsone gel, 5% for the treatment of acne vulgaris
  A new aqueous gel formulation of dapsone has been developed that allows clinically-effective doses of dapsone to be administered topically with minimal systemic absorption...   |   Read more ...



• 2007.8(1) A randomized, controlled, split-face clinical trial of 1320-nm Nd:YAG laser therapy in the treatment of acne vulgaris
  There is a need for additional effective treatments for acne vulgaris. Laser therapy has been explored as a therapeutic option for acne, but rigorously designed studies in this area have been limited...   |   Read more ...

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The Derm News service provided by the Editorial Consultants of Skin Therapy Letter^© and its founding editor Dr. Stuart Maddin.