Clindoxyl® Gel (Clindamycin phosphate and benzoyl peroxide) - A - Detailing from Skin Therapy Letter

 

Clindoxyl® Gel (Clindamycin phosphate and benzoyl peroxide)

 

 

  Content:

EFFICACY

 

 

The following figures show pooled data from randomized, controlled double-blind trials involving 673 patients with acne:


Reduction in non-inflammatory acne lesions after 11 weeks

Clindoxyl Gel 32%
Clindamycin alone 10%
Benzoyl peroxide 25%
Vehicle 1%

Reduction in inflammatory acne lesions after 11 weeks

Clindoxyl Gel 53%
Clindamycin 37%
Benzoyl peroxide 37%
Vehicle 14%

Percentage of patients in the clinical trials with good to excellent improvement

Clindoxyl Gel 51%
Clindamycin 40%
Benzoyl peroxide 38%
Vehicle 20%

REFERENCES:

[ Lookingbill DP et al. J Am Acad Derm 37(4):590-5(1997 Oct)]

Treatment of acne with a combination of clindamycin/benzoyl peroxide gel compared with clindamycin gel, benzoyl peroxide gel, and vehicle gel: combined results of two double blind investigations.

[Tan J.K.L. Clindoxyl Gel for the Treatment of Acne Vulgaris:]
Skin Therapy Letter Vol 7 No.5 May 2002


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