Clindoxyl® Gel (Clindamycin phosphate and benzoyl peroxide)
Content:
EFFICACY
The following figures show pooled data from randomized, controlled double-blind trials involving 673 patients with acne:
Reduction in non-inflammatory acne lesions after 11 weeks
| Clindoxyl Gel | 32% |
| Clindamycin alone | 10% |
| Benzoyl peroxide | 25% |
| Vehicle | 1% |
Reduction in inflammatory acne lesions after 11 weeks
| Clindoxyl Gel | 53% |
| Clindamycin | 37% |
| Benzoyl peroxide | 37% |
| Vehicle | 14% |
Percentage of patients in the clinical trials with good to excellent improvement
| Clindoxyl Gel | 51% |
| Clindamycin | 40% |
| Benzoyl peroxide | 38% |
| Vehicle | 20% |
REFERENCES:
[ Lookingbill DP et al. J Am Acad Derm 37(4):590-5(1997 Oct)]
Treatment of acne with a combination of clindamycin/benzoyl peroxide gel compared with clindamycin gel, benzoyl peroxide gel, and vehicle gel: combined results of two double blind investigations.
[Tan J.K.L. Clindoxyl Gel for the Treatment of Acne Vulgaris:]
Skin Therapy Letter Vol 7 No.5 May 2002
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