Diane-35 (2mg cyproterone acetate and 0.035mg ethinyl estradiol) - A - Detailing from Skin Therapy Letter


Diane-35 (2mg cyproterone acetate and 0.035mg ethinyl estradiol)







Suitable Candidates

  • Women who have acne associated or not with signs of hyperandrogenism
  • Any woman who has acne that is not controlled with topical medication
  • Used as a contraceptive during the use and after treatment with oral Isotretinoin. In Canada the drug is labelled for acne treatment but is entirely effective as a contraceptive and is indeed licensed as such in many countries
  • Women whose acne has flared after adolescence

Unsuitable Candidates

  • As with all estrogen/progestogen combinations, Diane-35 should not be prescribed to women who have thrombophlebitis, thromboembolic disorders or a history of these conditions
  • Women who wish to use Diane-35 for its contraceptive properties alone
  • Women who have any contraindication to the use of the birth control pill

  • Women who have:
    • unusual vaginal bleeding that has not yet been diagnosed
    • blood clots in the legs, lungs, eyes or elsewhere
    • a history of stroke, heart attack or chest pain
    • known or suspected cancer of the breast or sex organs
    • liver tumor associated with the use of the pill or other estrogen-containing products
    • jaundice or liver disease
    • Women who smoke and are older than 35 should use an alternate treatment for acne due to the increased risk of circulatory and metabolic complications with oral contraceptives

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