Elidel® (Pimecrolimus) - Detailing from Skin Therapy Letter


Elidel® (Pimecrolimus)







Mild to moderate atopic dermatitis (AD) in subjects 2 years of age and older

Label: ELIDEL is indicated for short-term and intermittent long-term therapy for mild to moderate atopic dermatitis in non-immunocompromised patients 2 years of age and older, in whom the use of alternative, conventional therapies is deemed inadvisable because of potential risks, inadequate clinical response, or patient intolerance of such therapies. It should not be applied to areas of active cutaneous infections. Patients should minimize or avoid natural or artificial sunlight exposure.

Reference: www.ca.pharma.novartis.com/downloads/e/elidel_scrip_e.pdf

Guidelines for Care of Atopic Dermatitis

  • Emollients are a standard of care, steroid-sparing, and useful for both prevention and maintenance therapy”
  • Pimecolimus and tacrolimus and has been shown to reduce the extent, severity and symptoms of AD in children and adults
  • Information is lacking as to the best way that these drugs can be combined with topical corticosteroids to maximise efficacy, minimize side-effects and reduce costs to the patient

Reference: JAAD 2004;50:391-404 Role of Calcineurin inhibitors

Use of Elidel in other inflammatory diseases

Elidel has been utilized in a small number of patients with:

  • Alopecia areata
  • Allergic contact dermatitis including poison ivy
  • Chronic hand dermatitis
  • Cutaneous lupus
  • Cutaneous Graft-Versus-Host Disease
  • Eyelid dermatitis
  • Facial angiofibromas
  • Lichen aureus
  • Lichen planus (oral)
  • Lichen sclerosus
  • Psoriasis
  • Rosacea
  • Seborrheic dermatitis
  • Vitiligo

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