Acne

Read articles related to acne, its symptoms, management, and treatment options.

Acne Treatment: Combination Topical Products

Combination therapy is a strategy of combining antibiotic treatments with other treatments with different mechanisms of action to treat acne. This has the effect of preventing or mitigating the unwanted effects of antibiotic resistant bacteria, and may confer other benefits such as lower required dosage as well.

Topical Acne Therapy: Current and Advanced Options for Optimizing Adherence

Topical treatment is the mainstay for mild acne, and adjunctive to oral or hormonal therapy for moderate acne. This article explores recent formulary advances and offers clinical strategies that can encourage adherence and improve treatment outcomes.

US FDA Advisory Committee Meetings Held to Discuss Isotretinoin, Safety Issues and a New Accutane Formulation

There is no drug that has provided as much therapeutic benefit for 12 million acne patients as this retinoid has done in the past 18 years following its introduction. However, it is a retinoid and, therefore, a teratogen.

Erythromycin 3% & Benzoyl peroxide 5% Gel for Acne

Benzoyl peroxide 5% plus erythromycin 3% (Benzamycin. gel, Dermik) will be evaluated. Although it is not known how effective it is compared with benzoyl peroxide and erythromycin prescribed separately, Benzamycin® is simpler to use and likely to improve patient compliance.

How Oral Contraceptives’ Progestins Influence Acne

This article organizes contraceptive pills is to compare the effects that the progestins that are used will have on acne.

Novel Topical Drug Delivery Systems and Their Potential Use in Acne Vulgaris

A vast spectrum of topical anti-acne agents has emerged in response to new insights that have been gained through the understanding of disease pathophysiology and the need for clinicians to adopt an individualized therapeutic approach.

Advances in Understanding Atrophic Acne Scarring and the Role of Adapalene/Benzoyl Peroxide

There have been important advances in our understanding of acne scarring. Acne scars can resolve, and their evolution is determined by a balance between matrix repair and degradation. Timely, effective management of acne can minimize risk of subsequent acne scarring.

Management of Recalcitrant Acne

Acne treatment success involves a comprehensive approach that addresses diagnostic confounders, appropriate therapeutic options and patient adherence. Ongoing education and counselling will assist in meeting patient expectations and establishing a favourable rapport that promotes adherence.

Adjunctive Skin Care for Acne (Pharmacist Edition)

Acne is among the most common dermatological disorders seen by dermatologists, affecting approximately 85% of people between the ages of 12 and 24 years. The use of adjunctive cleansers and moisturizers can help mitigate treatment side effects and subsequently enhance therapeutic efficacy.

Newer Approaches in Topical Combination Therapy for Acne

Acne vulgaris is a common chronic inflammatory cutaneous disease involving the pilosebaceous unit. This article discusses the multifactorial nature of acne pathophysiology, therapeutics, and mechanism of action.

A Novel Topical Retinoid for Acne: Trifarotene 50 μg/g Cream

In two large randomized vehicle-controlled 12-week trials and in a 52-week open label study of moderate-to-severe acne at the face and trunk in subjects aged 9 years and older, trifarotene 50 μg/g cream demonstrated efficacy, safety, and cutaneous tolerability.

Acne Treatment: Side-effects of Birth Control Pills

Oral contraceptives can have side-effects that are undesirable. Common and rare side-effects, contraindications, and possible drug interactions.

Dapsone 5% Gel: A New Option in Topical Therapy for Acne

Dapsone 5% gel for the topical treatment for acne represents the first new anti-acne agent to gain North American regulatory approval in the past decade. Dapsone's utility is attributable to its anti-inflammatory and antimicrobial properties, with more prominent effects occurring in inflammatory lesions.

Doxycycline as Acne Treatment Option

Doxycycline is a tetracycline antibiotic which is used to treat acne for its antibacterial and anti-inflammatory effects. Mechanism of action, side-effects, drug interactions, and various brands were discussed.

Sarecycline: A Narrow-Spectrum Antibiotic

Sarecycline is a novel antibiotic that has shown significant promise in acne treatment due to its narrow-spectrum activity and weight-based dosing.

Topical Acne Treatment

Management of the patients’ expectations and compliance are crucial aspects of acne treatment. Disease chronicity and long-term treatment should be discussed at length during the initial consultation.

Topical Treatment for Acne: A Case Study

Since patient compliance is a concern, a great deal of attention must be given to the methods available to minimize the chance of irritation. In the opinion of the author, this may be the single most important factor influencing the success of topical therapy in acne.

Tazarotene as Acne Treatment Option

Tazarotene is a designer retinoid. It is approved by Health Canada as a treatment for psoriasis, acne, and photodamage. This article discussed its indications, side-effects, use, and drug interactions.

Advances in Topical Acne Therapy: New Molecules, Vehicles and Delivery Mechanisms

Acne vulgaris is a multifactorial disease characterized by different types of lesions at various stages of development. The most frequently used therapeutic agents for acne are topical. This article focuses on the role of vehicles and advancements in this area.

A Clinician’s Guide to Treating Acne

In this article, we provide a guide to address a growing need by primary care physicians to have a logical and practical approach to treating various forms of acne.

Adherence Optimization in Acne Management

Acne is a common dermatological condition found in about 85% of adolescents and young adults. Acne can have significant psychological, social or physical impacts. This article delves into the importance of patinet adherence and therapeutic strategies.

Topical Tazarotene Therapy for Psoriasis, Acne Vulgaris, and Photoaging

Psoriasis, acne vulgaris and photoaging are common conditions. Tazarotene is a pro-drug of tazarotenic acid, a receptor-selective retinoid, which has shown efficacy in the treatment of these disorders. In the treatment of acne vulgaris, it has greater comedolytic activity than the currently available topical retinoids.

Does Diet Really Affect Acne?

A review of studies, reviewing association between a high-glycemic-load diet, hormonal mediators, and acne risk.

A Review of Systemic Retinoid Therapy for Acne and Related Conditions

Oral isotretinoin, since its introduction more than 20 years ago, has been and still is the 'gold standard' in the treatment of acne and its variants. This is the only approach to acne with the possibility of a permanent “cure” or long term remission.

Minocycline as Acne Treatment Option

Minocycline is a tetracycline antibiotic which is used for acne treatment. This article provides an overview of minocycline, side-effects, brands, and drug interactions are discussed.

Adapalene as Acne Treatment

Adapalene is a designer retinoid, with a similar molecular make-up with vitamin A. A guide to patient use, at what point in time should patients expect improvement, mechanism of action, side-effects, and other drug interactions are discussed in this article.

Update on Topical Acne Treatments

Topical acne treatment can positively benefit patients with acne. This review summarizes clinical and prescribing information on currently available topical agents. The efficacy of the medications included in this report is supported by properly designed randomized clinical trials.

A Controversial Proposal: No More Antibiotics for Acne!

Administration of antibiotics, often for prolonged periods, has become the standard of care for acne. The authors provide current evidence to suggest that dermatologists should consider a departure from standard operating procedure by curtailing, if not discontinuing, the routine and regular use of antibiotics for acne.

Psychosocial Impact of Acne Vulgaris: Evaluating the Evidence

This paper reviews current evidence presented by recent studies on the impact of acne on psychosocial health. Effective treatment of acne was accompanied by improvement in self-esteem, affect, obsessive-compulsiveness, shame, embarrassment, body image, social assertiveness and self-confidence.

Using Androgen Blockers for Acne Treatment

Anti-androgens are drugs that block the receptors which allow your body’s cells to absorb the male hormones. The indications of these drugs, side-effects, and contraindications are discussed in this article.

Advances in Acne Management and Patient Adherence

Acne vulgaris is a multifactorial disease characterized by different types of lesions at various stages of development. Treatment options, such as light based therapy and systemic therapy, as well as CIS-Isotretinoin (Epuris™) that increases absorption are discussed as well as patient adherence.

The Therapeutic Potential of Cannabinoids in Dermatology

Learn about cannabinoids influence on skin growth control, homeostasis, melanoma, acne, pruritus, inflammation, atopic dermatitis, and other skin conditions.

Combination Therapy for Acne Vulgaris

Acne vulgaris remains a therapeutic challenge, in large part due to its multifactorial pathophysiology. Evidence for improved and quicker efficacy with safety and longer remission has been noted with combination therapies.

Acne in the Post-Adolescent Patient

For the purposes of this article, the focus will be on the topical treatment of post-adolescent mild to moderate acne. A selection of over-the-counter and prescription based topical treatments are discussed below.

Topical Approaches in Combination Therapy for Acne (FP Edition)

Acne vulgaris is a chronic inflammatory cutaneous disease involving the pilosebaceous unit. This article discusses pathophysiology, sebum production, keratinization, and the role of P.acnes in acne formation.

The Impact of Acne on Quality of Life

Optimal acne therapy must take into account not only acne type and severity, but also the impact of this skin disorder on the patient’s quality of life.

Acne Treatment: Other Types of Birth Control Pills

Progestin only and combination pills are discussed in this article. Monophasic, biphasic, and triphasic pills are considered and listed.

The Role of Skin Care in Optimizing Treatment of Acne and Rosacea

A triad approach to the treatment of acne and rosacea has been recommended. This integrated management approach includes patient education, selection of therapeutic agents, and initiation of an appropriate skin care regime. Appropriate skin care recommendations for patients with acne and rosacea will be discussed.

Topical Acne Therapy Advances in 2011

Acne vulgaris is a common disorder of the pilosebaceous follicle with multiple pathogenic factors. Topics like antibiotic treatment, antibiotic resistant, topical agents, are covered.

Natural Topical Retinoids with Emphasis on Tretinoin for the Treatment of Acne

Topical retinoids are the cornerstone of acne therapy and they can be used across the entire spectrum of acne severity. Selecting the most suitable retinoid formulation, as well as dispensing proper advice in terms of drug application, can improve patient compliance.

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