Acne

Read articles related to acne, its symptoms, management, and treatment options.

Other Hormone Therapy’s Progestins’ Influence On Acne

Progestins have multiple influences on acne. Cyproterone acetate, found in Diane-35® seems to be an exception in that it is not affected by estrogen.

Advances in Understanding Atrophic Acne Scarring and the Role of Adapalene/Benzoyl Peroxide

There have been important advances in our understanding of acne scarring. Acne scars can resolve, and their evolution is determined by a balance between matrix repair and degradation. Timely, effective management of acne can minimize risk of subsequent acne scarring.

Perspectives on Isotretinoin and the Canadian Consensus Guidelines on Treatment of Acne

Treatment objectives and pharmacoeconomic considerations are important when developing guidelines that are effective and rational. Canadian Acne Treatment Guidelines were last published in 1995. New guidelines were recently developed to incorporate therapeutic advances and data from more recent studies.

Platelet-Rich Plasma (PRP): Current Applications in Dermatology

Platelet-rich plasma (PRP) is an autologous serum containing high concentrations of platelets and growth factors. PRP continues to evolve as an important treatment modality with many applications in dermatology, particularly in the areas of hair restoration, skin rejuvenation, acne scars, dermal augmentation, and striae distensae.

Different Types Of Acne Scars

Scars are a common problem that is often caused by acne. Various classifications of acne scars and their treatments and expectations are discussed.

Novel Topical Drug Delivery Systems and Their Potential Use in Acne Vulgaris

A vast spectrum of topical anti-acne agents has emerged in response to new insights that have been gained through the understanding of disease pathophysiology and the need for clinicians to adopt an individualized therapeutic approach.

Update on Topical Acne Treatments

Topical acne treatment can positively benefit patients with acne. This review summarizes clinical and prescribing information on currently available topical agents. The efficacy of the medications included in this report is supported by properly designed randomized clinical trials.

Tazarotene as Acne Treatment Option

Tazarotene is a designer retinoid. It is approved by Health Canada as a treatment for psoriasis, acne, and photodamage. This article discussed its indications, side-effects, use, and drug interactions.

The Impact of Acne on Quality of Life

Optimal acne therapy must take into account not only acne type and severity, but also the impact of this skin disorder on the patient’s quality of life.

Using Androgen Blockers for Acne Treatment

Anti-androgens are drugs that block the receptors which allow your body’s cells to absorb the male hormones. The indications of these drugs, side-effects, and contraindications are discussed in this article.

Newer Approaches in Topical Combination Therapy for Acne

Acne vulgaris is a common chronic inflammatory cutaneous disease involving the pilosebaceous unit. This article discusses the multifactorial nature of acne pathophysiology, therapeutics, and mechanism of action.

Optimizing Topical Acne Therapy (Pharmacist Edition)

This article discusses the rationale behind various topical treatments for acne to increase adherence and optimize outcomes. Efficacy, safety, antibiotic resistance, onset of action, and combination therapies are covered.

Topical Acne Treatment

Management of the patients’ expectations and compliance are crucial aspects of acne treatment. Disease chronicity and long-term treatment should be discussed at length during the initial consultation.

A Novel Topical Retinoid for Acne: Trifarotene 50 μg/g Cream

In two large randomized vehicle-controlled 12-week trials and in a 52-week open label study of moderate-to-severe acne at the face and trunk in subjects aged 9 years and older, trifarotene 50 μg/g cream demonstrated efficacy, safety, and cutaneous tolerability.

Acne Treatment: Side-effects of Birth Control Pills

Oral contraceptives can have side-effects that are undesirable. Common and rare side-effects, contraindications, and possible drug interactions.

Topical Tazarotene Therapy for Psoriasis, Acne Vulgaris, and Photoaging

Psoriasis, acne vulgaris and photoaging are common conditions. Tazarotene is a pro-drug of tazarotenic acid, a receptor-selective retinoid, which has shown efficacy in the treatment of these disorders. In the treatment of acne vulgaris, it has greater comedolytic activity than the currently available topical retinoids.

Adapalene as Acne Treatment

Adapalene is a designer retinoid, with a similar molecular make-up with vitamin A. A guide to patient use, at what point in time should patients expect improvement, mechanism of action, side-effects, and other drug interactions are discussed in this article.

Improving Bioavailability with a Novel Isotretinoin Formulation (Isotretinoin-Lidose)

Current practice guidelines recommend administration of oral isotretinoin with high-fat meals, which may pose issues with patient compliance. This article discusses Isotretinoin-Lidose (Epuris™), pharmacokinetics, bioavailability, and increased drug absorption rate, and how it may improve patient compliance.

Management of Recalcitrant Acne

Acne treatment success involves a comprehensive approach that addresses diagnostic confounders, appropriate therapeutic options and patient adherence. Ongoing education and counselling will assist in meeting patient expectations and establishing a favourable rapport that promotes adherence.

US FDA Advisory Committee Meetings Held to Discuss Isotretinoin, Safety Issues and a New Accutane Formulation

There is no drug that has provided as much therapeutic benefit for 12 million acne patients as this retinoid has done in the past 18 years following its introduction. However, it is a retinoid and, therefore, a teratogen.

Isotretinoin (Accutane®) as Acne Treatment

Isotretinoin (Accutane®) is a retinoid or vitamin A analog, which means that its molecular structure is similar to Vitamin A. Mechanism of action, efficacy, side-effects, and contraindications are discussed as well as an FAQ section for this drug.

Polycystic Ovary Syndrome and Acne

Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in reproductive aged women. This article will review the treatments for acne due to androgen excess in PCOS women.

Systemic Antibiotic Therapy for Acne: A Review

Acne is a multifactorial disease of the pilosebaceous unit in the skin. Four contributing pathogenic factors need to be elucidated and include excess sebum production, follicular hyperkeratinization, colonization of the pilosebaceous unit by Propionibacterium acnes.

Topical Acne Therapy: Current and Advanced Options for Optimizing Adherence

Topical treatment is the mainstay for mild acne, and adjunctive to oral or hormonal therapy for moderate acne. This article explores recent formulary advances and offers clinical strategies that can encourage adherence and improve treatment outcomes.

Oral Antibiotics For Acne Treatment

Oral antibiotics are an important treatment option that is available for treating inflammatory acne. This portal provides an organized list of the most commonly used oral antibiotics for the treatment of acne.

A Review of Systemic Retinoid Therapy for Acne and Related Conditions

Oral isotretinoin, since its introduction more than 20 years ago, has been and still is the 'gold standard' in the treatment of acne and its variants. This is the only approach to acne with the possibility of a permanent “cure” or long term remission.

Topical Clascoterone for Acne Vulgaris

Clascoterone 1% cream represents a novel and promising therapeutic agent in the management of acne vulgaris for individuals ≥12 years of age. Notably, this topical agent was not observed to have significant systemic effects seen with systemic anti-androgenic agents.

The Treatment of Cystic Acne

Cystic acne is characterized by the formation of cysts enclosing a mixture of keratin and sebum in varying proportions. It is the most severe of the four main types of acne, which are comedonal, papular, pustular, and cystic. Identification and treatment options are discussed.

Acne Treatment: Understand Your Patient’s Options

A brief discussion of treatment options that are available for various patients. Factors like severity, type of acne, response to previous treatment that are unique to the patient can influence the best course of treatment.

How Oral Contraceptives’ Progestins Influence Acne

This article organizes contraceptive pills is to compare the effects that the progestins that are used will have on acne.

Oral Contraceptives in the Treatment of Acne

Oral contraceptives (OCs) can reduce acne by lowering the production of adrenal and ovarian androgens, by inhibiting 5- alpha-reductase, which in turn, reduces the levels of dihydrotestosterone, and by stimulating sex hormone binding globulin (SHBG), thus reducing the levels of free testosterone.

Acne: Maximizing Effectiveness With Combination Therapy

Educate and counsel. Most patients with acne are teenagers who are very self-conscious about their looks and expect immediate treatment results. However, adult acne is becoming more common, and can be very distressing as well.

Tazarotene Lotion 0.045% for the Treatment of Acne

Tazarotene 0.045% lotion is a novel formulation which utilizes polymeric emulsion technology to improve tolerability and epidermal penetration. Despite the lower concentration of tazarotene in the lotion formulation, which likely also contributes to improved tolerability, tazarotene 0.045% lotion is at least as effective as tazarotene 0.1% cream.

Efficacy of Lasers and PDT for the Treatment of Acne Vulgaris

Acne vulgaris can represent a therapeutic challenge in terms of managing ongoing symptoms and preventing scar formation. Dermatologists may now have viable new alternatives for treating all grades of acne severity that circumvent the negative side-effects associated with many conventional options.

The Role of Skin Care in Optimizing Treatment of Acne and Rosacea

A triad approach to the treatment of acne and rosacea has been recommended. This integrated management approach includes patient education, selection of therapeutic agents, and initiation of an appropriate skin care regime. Appropriate skin care recommendations for patients with acne and rosacea will be discussed.

The Therapeutic Potential of Cannabinoids in Dermatology

Learn about cannabinoids influence on skin growth control, homeostasis, melanoma, acne, pruritus, inflammation, atopic dermatitis, and other skin conditions.

The New Canadian Guideline for Acne Treatment

Physicians will be particularly reassured if the suggested guidelines are supported by scientific evidence. This new Canadian clinical guideline for the treatment of acne was developed taking into account new data published up to March 2015, as well as expert opinion and clinical experience.

Laser Management of Acne Scarring

Acne scarring is often challenging to manage. This article discusses various laser treatments that are helpful in addressing abnormal color and texture in order to improve the appearance of an acne scar as well as review the appropriate use and side-effects of these treatments.

What’s New in Acne Treatment in Canada?

Acne vulgaris is the most common skin disorder affecting children and young adults in North America. This article discusses combination therapy, and simplifying treatment plans in order to increase patient adherence, which is often a critical problem in treating acne.

Topical Acne Therapy Advances in 2011

Acne vulgaris is a common disorder of the pilosebaceous follicle with multiple pathogenic factors. Topics like antibiotic treatment, antibiotic resistant, topical agents, are covered.

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