Aging Skin

Read articles related to aging skin, environmental and genetic factors that are relevant, and more.

Understanding Facial Aging: Non-Linear Aging Process

Why is it that some people (other people!) seem to age slower? It's not fair! Plastic surgeon Dr. Bryce Cowan explains the complexities and factors that affect the timeline of aging, in the first part of the Science of Facial Aging series.

Markers of Facial Aging

Plastic surgeon Dr. Bryce Cowan explains the two primary processes that affect facial aging simultaneously - volume loss, and malposition.

How does Aging of the Face Manifest Itself?

The upper, mid, and lower face all age as we go through the decades. Dr. Bryce Cowan explains how symptoms of aging typically manifest over time.

Face Aging: Decade by Decade

The upper, mid, and lower face all age as we go through the decades. Dr. Bryce Cowan explains how symptoms of aging typically manifest over time.

Treatment Options for Facial Aging

Can you reverse the aging process? Dr. Bryce Cowan gives us the truth about aging, cosmetic surgery, and the difference between non-invasive procedures like Botox/fillers vs cosmetic surgery.

Debunking Common Misconceptions about Aging Process

What cosmetic procedures might be useful for a given patient? The two key principles of aging of the face are volume loss and tissue malposition. There are many elements changing simultaneously, so it's very rare that there is an effective singular procedure that can act as a fix all solution.

Botox, Injectable Filler, and Cosmetic Surgery to Treat Aging Face

What cosmetic procedures might be useful for a given patient? The two key principles of aging of the face are volume loss and tissue malposition. There are many elements changing simultaneously, so it's very rare that there is an effective singular procedure that can act as a fix all solution.

Advantages of Cosmetic Surgery when Treating Aging Face

What are the advantages of cosmetic surgery over soft procedures like Botox and dermal fillers? The main advantage is that cosmetic surgery allows for a more profound and long lasting correction that's not possible with other treatment options.

Who Would be the Ideal Candidate for Cosmetic Surgery to treat Aging Face

The ideal candidate depends on the specific treatment, but in general terms, we are looking at a patient who is a healthy, non-smoker, does not have high blood pressure, does not require anti-coagulants, is in their late 40s or early 50s, where the impact of the surgery is highest.

Unfit Candidates for Cosmetic Surgery

Patients need to be able to both understand and accept the risks of surgery. It's a balance between their motivation and desire to undergo surgery and their willingness to accept the risks involved with that procedure.

The Cost of Treating Aging Face

Patients need to be able to both understand and accept the risks of surgery. It's a balance between their motivation and desire to undergo surgery and their willingness to accept the risks involved with that procedure.

Patient Research: How Would Patients Choose Their Surgeon?

Patients need to be able to both understand and accept the risks of surgery. It's a balance between their motivation and desire to undergo surgery and their willingness to accept the risks involved with that procedure.

Sugar Sag: Glycation and the Role of Diet in Aging Skin

Increased accumulation of AGEs in human tissue has been associated with serious medical concerns including end stage renal disease, chronic obstructive pulmonary disease, and, recently, skin aging. In this review, we summarize the evidence supporting the role of glycation in skin aging.

Sirolimus: A Therapeutic Advance for Dermatologic Disease

Sirolimus, also known as rapamycin (SRL, Rapamune®), was approved in 1999 by the US Food and Drug Administration to prevent graft rejection in renal transplantation. This articles reviews Sirolimus, its pharmacokinetics, mechanism of action, and indication.

Age-related Percutaneous Penetration Part 2: Effect of Age on Dermatopharmacokinetics and Overview of Transdermal Products

Transdermal drug delivery allows for a constant rate of drug administration. This second part highlights the importance of elderly patient care, and consideration for patients who may be using multiple drug treatments.

Age-related Percutaneous Penetration Part 1: Skin Factors

Changes in the skin that occur in the elderly may put them at increased risk for altered percutaneous penetration from pharmacotherapy along with potential adverse effects. This overview discusses the current data of studies to evaluate the impact of skin factors in age-related percutaneous penetration.

Botulinum Toxin Type A: New Information about an Old Medicine

Several formulations of botulinum toxin type-A (BoNT-A) are on the market in North America. This article discusses formulations, and differences in pharmacokinetics, and how it affects indications.

Practical Application of Genomics to the Development of a Topical Cosmetic Anti-aging Regimen

The development of topical cosmetic anti-aging products is becoming increasingly sophisticated. This article reviews trials that look at the efficacy of cosmetic (OTC) products against prescription products.

The Multifunctional Value of Sunscreen-containing Cosmetics

Cosmetic products containing ultraviolet light filtering agents are rapidly being developed and entering the marketplace. This article reviews formulary attributes, effective photoprotection, adherence, and behavior modification.

The Management of Chronic Pruritus in the Elderly

The elderly in North America is the fastest growing segment of the population and their most common skin complaint is pruritus. This article outlines the therapeutic challenges with this population.

Smoking and Skin Disease

Tobacco smoking is a serious and preventable health hazard that can cause or exacerbate a number of diseases and shorten life expectancy. This article delves into the role of smoking as an etiologic factor in the development of skin disease.

Predictive Testing of the Melanocortin 1 Receptor for Skin Cancer and Photoaging

Genetic predisposition to melanoma and nonmelanoma skin cancer extends far beyond the Fitzpatrick phenotype classification scheme. Testing aimed at improving prognostication may serve to limit the influence of certain risk factors.

Prevention of Infrared-A Radiation Mediated Detrimental Effects in Human Skin

Photoaging and skin damage that is caused by solar radiation is well known. IRA acts via the mitochondria and therefore protection from IR requires alternative strategies.

The Role of Cosmeceuticals in Antiaging Therapy

As baby boomers get older, they have shown an increasing interest in maintaining a youthful appearance. This paper reviews the more common cosmeceutical ingredients.

Antioxidants Used in Skin Care Formulations

The formation of free radicals is a widely accepted pivotal mechanism leading to skin aging. Topical antioxidants are available in multivariate combinations through over-the-counter skin care products that are aimed at preventing the clinical signs of photoaging.

Botulinum Toxin Products Overview

The success of botulinum toxin type A (BOTOX®, Allergan Inc.) in the cosmetic arena has acted as a stimulus for the development of other neurotoxins. Herein, we present an overview of botulinum toxin products for cosmetic applications that have received regulatory approval or are under development.

The Role of Cosmeceuticals in Anti-Aging Therapy

As baby boomers get older, they have shown an increasing interest in maintaining a youthful appearance. As a result, there has been a corresponding increase in topical antiaging formulations, which are commonly referred to as cosmeceuticals.

Concepts in a Multiprong Approach to Photoaging

Photoaging is a multisystem degenerative process that involves the skin and the skin support systems, including the bone, cartilage, and subcutaneous compartments. These structures provide the architectural support for the dermis, epidermis, and stratum corneum.

Reduction of Face and Neck Laxity With Anchored, Barbed Polypropylene Sutures (Contour Threads™)

The use of nonabsorbable sutures for lifting lax, aging skin is an increasingly popular option for cosmetic surgeons. Contour Threads™ (Surgical Specialties Corp.) are novel modified polypropylene sutures recently approved for this purpose by the US FDA.

Skin Conditions and the Sun

The skin has evolved to protect us from the harmful effects of ultraviolet light. Sunscreens were first developed to prevent sunburns by blocking UVB; they allowed us to prolong our time in the sun, but that resulted in increased exposure to UVA.

Treatment of Photoaging with Topical Aminolevulinic Acid and Light

Photodynamic therapy has been used for several years for the treatment of actinic keratoses and prevention of invasive nonmelanoma cancers. Recently, increasing physician expertise with the topical sensitizers and light sources employed in PDT has led to expanded applications.

Topical Tazarotene Therapy for Psoriasis, Acne Vulgaris, and Photoaging

Psoriasis, acne vulgaris and photoaging are common conditions. Tazarotene is a pro-drug of tazarotenic acid, a receptor-selective retinoid, which has shown efficacy in the treatment of these disorders. In the treatment of acne vulgaris, it has greater comedolytic activity than the currently available topical retinoids.

Update on the Botulinum Neurotoxins

The botulinum neurotoxins (BTX) are an exciting group of therapeutic agents with dramatically expanding clinical indications. The US FDA has approved BOTOX® (BTX-A, Allergan) and Myobloc™ (BTX-B, Elan Pharmaceuticals) for the treatment of cervical dystonia.

Soft Tissue Augmentation with Silicone

Adatosil® is a viscous silicone oil which was granted FDA approval in 1994. This designation removes the legal obstacles to usage for soft tissue augmentation. However, physicians are advised to exercise discretion when using this product.

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