STL Index for: Ruxolitinib
Extracorporeal Photopheresis and Its Use in Clinical Dermatology in Canada
Results from multiple studies have shown promising response rates, and extracorporeal photopheresis has an overall excellent safety profile with very few adverse events reported.
Update on Drugs & Devices: September – October 2022
Update covering: Roflumilast cream 0.3% (Zoryve™), Ruxolitinib cream 1.5% (Opzelura™), HA-based dermal filler (Juvéderm® Volux™ XC), Abrocitinib tablets (Cinbinqo®), LetibotulinumtoxinA for injection (Letybo®), Berotralstat capsules (Orladeyo®), Mogamulizumab IV infusion (Poteligeo®), and Avacopan capsules (Tavneos®).
Janus Kinase and Tyrosine Kinase Inhibitors in Dermatology: A Review of Their Utilization, Safety Profile and Future Applications
Currently, JAK inhibitors are only FDA approved for dermatologic, rheumatologic, and hematologic conditions. Recent studies show the utility of JAK inhibitors in treating atopic dermatitis, psoriasis, psoriatic arthritis, vitiligo, and alopecia areata.
Update on Drugs & Devices: November-December 2021
The update covers Difelikefalin for IV use - Korsuva™ (Vifor Pharma, Cara Therapeutics), Topical MEK inhibitor - NFX-179 (NFlextion Therapeutics), Maralixibat oral solution - Livmarli™ (Mirum Pharmaceuticals), Ruxolitinib cream 1.5% - Opzelura™ (Incyte), Ruxolitinib tablets - Jakafi® (Incyte), and Avacopan capsules - Tavneos™ (ChemoCentryx).
Dermatologic Applications and Safety Considerations of Janus Kinase Inhibitors
Janus kinase inhibitors, also known as JAK inhibitors or jakinibs, represent a new class of medication that have broad potential to treat dermatologic disease.
Update on the Management of Vitiligo
Vitiligo is a psychosocially debilitating disease requiring a multidisciplinary approach to treatment. Patients should be made aware of all of the options available geared at repigmentation and depigmentation prior to formulating a treatment plan.
Janus Kinase Inhibitors: A Review of Their Emerging Applications in Dermatology
The class of medications known as Janus kinase inhibitors block cytokine-mediated signaling via the Janus kinase-signal transducer and activator of transcription (JAK-STAT) pathway, which plays an important role in immunoregulation and normal cell growth.
Small Molecules: An Overview of Emerging Therapeutic Options in the Treatment of Psoriasis
While biologics changed the way psoriasis is treated by providing effective targeted therapy, they are not without limitations. Small molecules are emerging therapeutic options for the treatment of psoriasis.