STL Volume 4 Number 5
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Update on Drugs and Drug News: April, 1999
Update on: Mupirocin Bactroban® Roxithromycin Rulid® Temoporfin Foscan®Fluticasone propionate Cutivate® Cream 17-Beta-Estradiol Vagifem® Itraconazole injection Sporanox® IV injection Becaplermin Regranex® Gel 0.1% Lidocaine/prilocaine EMLA® cream
Soft Tissue Augmentation with Silicone
Adatosil® is a viscous silicone oil which was granted FDA approval in 1994. This designation removes the legal obstacles to usage for soft tissue augmentation. However, physicians are advised to exercise discretion when using this product.
N-2-butylcyanoacrylate (GluStitch™)
Cyanoacrylates are surgical adhesives that provide another option for wound closure. There are a number of surgical adhesives either currently available or under development. The presently available butylcyanoacrylates and octylcyanoacrylates are reviewed.
Update on Botulinum Toxin
Botulinum toxin type-A (BTX-A) is a neurotoxin which blocks presynaptic release of acetylcholine. It interferes with neuromuscular transmission, temporarily paralyzing the affected muscle. Of special interest for dermatologists is the unlabelled cosmetic applications, for conditions such as wrinkles and hyperhidrosis.