Ablative Laser Resurfacing – Postoperative Care

Wound care after laser skin resurfacing is critical for achieving a successful result. The superficial thermal injury created by laser skin resurfacing heals more quickly and with a reduced risk of scarring under occlusion. Effective management techniques can help minimize expected negative effects.

Mycophenolate Mofetil: A Dermatologic Perspective

Introduced in the 1970s as a treatment for psoriasis, mycophenolic acid has since been reformulated as mycophenolate mofetil (MMF). With an improved side-effect profile and enhanced bioavailability, MMF is a promising drug for immune-mediated skin disease.

Psoriasis, Depression, and Suicidality

Psoriasis is a chronic condition that affects the well-being and quality of life of patients. The disease is associated with an increased risk of depression and suicidality, which may not be fully understood by the general population.

Fractional Laser Treatment for Pigmentation and Texture Improvement

Fractional laser treatment with the 1,550nm erbium fiber laser (Fraxel® Laser, Reliant Technologies) has bridged the gap between the ablative and nonablative laser modalities used to treat the epidermal and dermal signs of skin aging.

Newer Approaches in Topical Combination Therapy for Acne

Acne vulgaris is a common chronic inflammatory cutaneous disease involving the pilosebaceous unit. This article discusses the multifactorial nature of acne pathophysiology, therapeutics, and mechanism of action.

Topical Diacerein Ointment for Epidermolysis Bullosa Simplex: A Review

This review examines the clinical trials of topical diacerein and its role in Epidermolysis Bullosa Simplex. Diacerein cream was recently US FDA-approved in May 2018 for treatment of patients with EBS.

Pigmentary Disorders in Asian Skin: Treatment With Laser and Intense Pulsed Light Sources

The development of selective photothermolysis has enabled removal of targets such as melanin. Both lasers and intense pulsed light (IPL) sources have been used in the treatment of pigmented lesions, however careful selection is important to ensure success.

Colloidal Oatmeal use in Dermatology (Supplement)

There is mounting evidence that colloidal oatmeal can safely enhance skin hydration and even help resolve clinical lesions through anti-inflammatory effects and by modulation of the microbiome.

Imiquimod Applied Topically: A Novel Immune Response Modifier

Imiquimod (S-26308, R-837) (1-(2-methylpropyl)-1H-imidazo[4,5-c]quinolin-4 amine), an immune response modifier, was approved as a 5% cream (Aldara, 3M Pharmaceuticals) by the US FDA in February 1997, for the treatment of genital and perianal warts.

Skin, Hair and Nail Supplements: An Evidence-Based Approach

Dermatology supplements, often marketed as “skin, hair, and nail” supplements, are becoming increasingly popular. However, many consumers lack an understanding of the science of dietary supplements or the specifics of the supplement industry.

Current Concepts in Laser Tattoo Removal

Today, more than 10% of the Western population has at least 1 tattoo, with prevalence of up to one-fourth in the cohort younger than 30 years of age. This article provides an overview of applicable laser systems and therapeutic strategies for optimized tattoo removal.

Update on Drugs & Devices: May-June 2018

Update on Drugs & Devices May and June 2018: Tildrakizumab-asmn for SC injection Ilumya™, Lidocaine topical system 1.8% for postherpetic neuralgia ZTlido™, Secukinumab for SC injection Cosentyx®, Vaginal gel for prevention of urogenital chlamydia Amphora®.

Update on Drugs & Devices: September – October 2019

The latest drug & device update covers: Adalimumab-bwwd for SC injection (Hadlima™), Apremilast tablets (Otezla®), Calcipotriene + betamethasone dipropionate (Enstilar® foam Taclonex® topical suspension), Bempegaldesleukin + nivolumab for IV use (NKTR-214 + Opdivo®), Dupilumab for SC injection (Dupixent®), Magnetic muscle stimulation for body contouring (CoolTone™), Laser device for body contouring (eon™ FR).

Update on Drugs and Drug News: November-December 2012

Update on drugs, approval dates, and comments. Poly-ureaurethane 16% nail solution (Nuvail™), Calcipotriene 0.005% foam (Sorilux™), Hyaluronic acid injectable gel (Restylane-L®) are covered.

Tavaborole 5% Solution: A Novel Topical Treatment for Toenail Onychomycosis

Onychomycosis is a stubborn fungal infection of the nails that can be difficult to manage. Clinical trial data of Tavaborole is considered, as it allows for effective nail penetration compared to ciclopirox and amorolfine lacquers.

Platelet-Rich Plasma (PRP): Current Applications in Dermatology

Platelet-rich plasma (PRP) is an autologous serum containing high concentrations of platelets and growth factors. PRP continues to evolve as an important treatment modality with many applications in dermatology, particularly in the areas of hair restoration, skin rejuvenation, acne scars, dermal augmentation, and striae distensae.

Oral Contraceptives in the Treatment of Acne

Oral contraceptives (OCs) can reduce acne by lowering the production of adrenal and ovarian androgens, by inhibiting 5- alpha-reductase, which in turn, reduces the levels of dihydrotestosterone, and by stimulating sex hormone binding globulin (SHBG), thus reducing the levels of free testosterone.

Nail Psoriasis: Treatment Options

Approximately 50% of patients with psoriasis have nail psoriasis but the life time chance of nail changes must be much higher. Nail changes in psoriasis include pitting, thickening, onycholysis, discoloration, oily spots, splinter hemorrhages and paronychia. Treatment of choice depends on the form the psoriasis takes.

Pediatric Psoriasis

Several variants of psoriasis are seen in children, the most prevalent types include plaque, guttate, and psoriatic diaper rash; pustular and erythrodermic psoriasis are less frequently observed. This article discusses genetic susceptibility, and environmental triggers are discussed.

Vulvovaginal Dryness and Itching

Dryness and itching in the vulvovaginal area is an increasing problem as our female population ages and becomes menopausal. This dryness and itching is often the result of estrogen deficiency, and there are typically two types of treatment: Specific Therapy (or hormone replacement therapy), and Nonspecific Therapy.

Male Aesthetics

Men are a fast growing segment of the aesthetic industry. This article discusses important gender differences in facial anatomy and behavior that are relevant, as well as the requirement for different injection techniques when using dermal fillers and Botulinum toxins.

Overview of Treatment of Vulvovaginal Disease

Vulvovaginal diseases commonly are inadequately diagnosed and treated. This article discusses the important role dermatologists play in identifying irregular presentations, recognizing skin problems, and addressing itch, pain, and inflammation.

Novel Agents for Intractable Itch

There exists a multitude of medical conditions that cause intractable itch, or pruritus. These novel antipruritic agents will be explored in this review.

Update on Drugs and Drug News: June 2002

Updates on: Tretinoin Gel Microsphere Retin-A® Micro 0.04% Cyclosporine capsules 25mg, 100mg Gabapentin Neurontin® Docosanol 10% Cream Salicylic Acid 15% Trans-Ver-Sal® Wart Removal Patch

Novel Dermatologic Uses of the Immune Response Modifier Imiquimod 5% Cream

Imiquimod is the first of a new class of drugs to emerge in the treatment of various dermatologic disorders. As an immune response modifier, it has been shown to have potent antiviral and antitumor properties through the stimulation of innate and cell mediated immune pathways.

Current Management of Scalp Psoriasis

The scalp is involved in up to 80% of individuals with psoriasis. Topical treatment with corticosteroids with or without vitamin D3 analogues is the mainstay of treatment, but other therapies such as light treatment and systemic drugs including biologics are discussed.

Silk Fabrics in the Management of Atopic Dermatitis

Many factors may worsen atopic dermatitis including sweating, skin infections, food, inhalant allergens, climatic conditions, stress, and chemical or physical irritants. This article delves into the role of clothing and fabrics that contact the skin in the management of atopic dermatitis.

Pimecrolimus and Tacrolimus: The US FDA Public Health Advisory

In February of this year, the US FDA issued a public health advisory to inform healthcare providers and patients about a potential cancer risk from the topical use of pimecrolimus (Elidel©, Novartis), approved by the FDA in December 2001, and tacrolimus (Protopic©, Astellas, formerly Fujisawa), approved in December 2000.

Drug Treatments For Skin Disease Introduced in 1999

Drug Treatments For Skin Disease Introduced in 1999

Management and Treatment of Pruritus

Pruritus, or itch, is a common sensation that causes a person to want to scratch. It is a complex process that may negatively impact quality of life. This overview provides information regarding the various management and treatment options for pruritus.

Diagnostics and Devices Introduced in 2011

An overview and update of diagnostics and devices introduced in 2011: HPV RNA detection kit APTIMA® HPV Assay, HPV DNA detection kit cobas® HPV Test cobas® 4800 System, Microwave-based device (miraDry®) for hyperhydrosis and many more drugs and devices are covered.

The Impact of Acne on Quality of Life

Optimal acne therapy must take into account not only acne type and severity, but also the impact of this skin disorder on the patient’s quality of life.

Therapeutic Update on Seborrheic Dermatitis

Seborrheic dermatitis is a recurrent, usually mild, skin disorder with typical clinical manifestations. This article will review the available treatments for this common dermatologic problem.

Update on Drugs and Drug News: September, 1998

Update on: Efavirenz Sustiva® Nevirapine Viramune®Famciclovir Famvir®Cetirizine Zyrtec® Rifapentine Priftin® Denileukin diftitox Ontak® Doxorubicin Caelyx® Graftskin Apligraf® Dangers of alternative medicine, Protease inhibitors during pregnancy

Update on Drugs and Drug News: November 2009

Updates on Ustekinumab Stelara® Centocor Ortho Biotech, Romidepsin ISTODAX® Gloucester Pharmaceuticals and news from US FDA.

Tacrolimus Ointment (Protopic®) for Atopic Dermatitis

Tacrolimus ointment (Protopic®, Fujisawa) is an effective agent in a class of topical immunomodulators. It has been shown to be safe and effective in adults and children with Atopic Dermatitis in short- and long-term treatments.

Update on Drugs & Devices: November – December 2019

The latest drug & device update covers: Trifarotene 0.005% cream (Aklief®, Galderma), Afamelanotide implant (Scenesse®, Clinuvel Pharmaceuticals), Rituximab for IV use (Rituxan®, Genentech), Jynneos™ (Bavarian Nordic), Aczone® (Almirall) and Juvéderm Voluma® XC (Allergan)

Treatments for Unwanted Facial Hair

Twenty-two percent of women in North America have unwanted facial hair, which can cause embarrassment and result in a significant emotional burden. Eflornithine 13.9% cream can be used in combination with other treatments such as lasers and IPL to give the patient the best chance for successful hair removal.

Chronic Idiopathic Urticaria: Treatment with Omalizumab

Omalizumab has emerged as a very promising treatment option for patients with CSU (Chronic spontaneous urticaria).This editorial reviews mechanisms of action of omalizumab, efficacy, cost and potential side effect profile.

Update on Drugs and Drug News: March-April 2015

Update on Human papillomavirus 9-valent vaccine, recombinant (Gardasil®9), Ivermectin 1% cream (Soolantra®), Naftifine HCl 2% gel & cream (Naftin®), Nivolumab IV infusion (Opdivo®), Polymethylmethacrylate collagen dermal filler for acne scars (Bellafill®), Secukinumab SC injection (Consentyx™).

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