Twelve Technical Strategies to the Perfect Surgical Scar

Achieving an excellent surgical result while managing disease can be a daunting task when the basic surgical principles we were all taught have been lost to time and the perpetuation of poor surgical habits that were adopted from others. Here are strategies that can help to improve your scar outcomes.

Update on Drugs & Devices: May-June 2021

The update covers: Axatilimab IV injection - SNDX-6352 (Syndax Pharmaceuticals), Binimetinib tablets + encorafenib capsules - Mektovi® + Braftovi® (Pfizer Canada), Encapsulated cell therapy for Fabry disease - SIG-007 (Sigilon Therapeutics) and Oritavancin IV injection - Kimyrsa™ (Melinta Therapeutics).

Update on Drugs & Drug News August 2005

Updates on: Infliximab Remicade®Cyproterone Ethinyl Diane-35

Recent Approval of Xerese in Canada: 5% Acyclovir and 1% Hydrocortisone Topical Cream in the Treatment of Herpes Labialis

Herpes labialis is a frequently occurring viral infection of the lips and oral mucosa. Clinical data on the efficacy of topical combination acyclovir-hydrocortisone (Xerese™) product in treating herpes labialis are discussed.

Calcipotriol and Betamethasone Dipropionate (Dovobet®, Daivobet®): A New Formulation for the Treatment of Psoriasis

A new compound product containing calcipotriol 50μg/gm and betamethasone dipropionate 0.5mg/gm (Dovobet*, LEO Pharma) in an ointment base was recently introduced in Canada for the treatment of psoriasis.

Hepatitis B and C Viruses and Biologics

Hepatitis B virus (HBV) and hepatitis C virus (HCV) potentially impact the clinician's ability to manage patients with immunosuppressive medications such as biological therapy. In light of recent literature reviews, patients with HBV and HCV should be referred to a hepatologist.

Concepts in a Multiprong Approach to Photoaging

Photoaging is a multisystem degenerative process that involves the skin and the skin support systems, including the bone, cartilage, and subcutaneous compartments. These structures provide the architectural support for the dermis, epidermis, and stratum corneum.

Update on Drugs and Drug News – May 2007

Update on Antiacne Agent Drospirenone/ Ethinyl Estradiol Yaz® Berlex, Corticosteroid Clobetasol Propionate 0.05% Olux-E™ Foam Stiefel Laboratories and news from US FDA.

Unanswered Questions in Antifungal Therapy for Onychomycosis

Onychomycosis has a significant impact on the patient. With three new, orally effective, antifungal agents, we have for the first time effective treatment that can provide benefit for a high percentage of patients. This review examines some of the areas of uncertainty and controversy.

Update on Drugs and Drug News: September-October 2017

September-October 2017 Update on drugs include Isopropyl myristate solution Resultz®, Delafloxacin oral and IV formulations Baxdela™, Plasma-derived concentrate of C1 esterase inhibitor SC (human) Haegarda®, Oral dimethyl fumarate Skilarence®, Abatacept for IV or SC injection Orencia®, Consentyx®, Tremfya™, Yervoy® and Benlysta®.

Moxifloxacin (Avelox®) For The Treatment Of Bacterial Skin Infections

Moxifloxacin (Avelox®, Bayer), which is available for oral administration, is a broad-spectrum synthetic antimicrobial agent with excellent Gram-positive activity and good Gram-negative activity. The US FDA recently approved this drug for the treatment of bacterial skin infections.

Rosacea

Clinical rosacea is not a single disease but rather a combination of cutaneous stigmata which include flushing, erythema, telangiectasia, facial edema, papules, pustules, ocular lesions, and rhinophyma. A review of rosacea, treatment, and management.

A Review of Systemic Retinoid Therapy for Acne and Related Conditions

Oral isotretinoin, since its introduction more than 20 years ago, has been and still is the 'gold standard' in the treatment of acne and its variants. This is the only approach to acne with the possibility of a permanent “cure” or long term remission.

Current Concepts in Laser Tattoo Removal

Today, more than 10% of the Western population has at least 1 tattoo, with prevalence of up to one-fourth in the cohort younger than 30 years of age. This article provides an overview of applicable laser systems and therapeutic strategies for optimized tattoo removal.

Human Skin Equivalent (HSE) , Apligraf Part II Clinical Use

Preparation of the wound bed, proper application of Apligraf, and patient compliance with underlying therapy for underlying disease are probably the most important determinants of clinical efficacy. Part 2 of the series.

Systemic Retinoids: Chemoprevention of Skin Cancer in Transplant Recipients

Solid organ transplant recipients have an increased incidence of skin cancer, resulting in significant morbidity and mortality post-transplantation. This article studies systemic retinoids, and other chemopreventative agents for high risk patients.

Systemic Drugs With Antipruritic Potency

There are no specific antipruritic drugs on the market, but there are a high number of case reports and experimental investigations describing medications with antipruritic potency. It is therefore the aim of this article to review the major systemic antipruritic drugs and give a short overview on the different types of pruritus.

Sunscreens in the Management of Photodermatoses

Key to the management of photodermatoses is photoprotection, which includes seeking shade; wearing wide brimmed hats, and sunglasses; and applying sunscreens. This article discusses sunscreens, sun protection, UVA, UVB, and its role in managing various skin conditions.

Management of the Ichthyoses

The ichthyoses are a heterogeneous group of inherited scaling skin disorders that can also affect other organs. Management should be directed at both the skin and other sites. Skin therapy is not specific at this time, although new products may offer more directed therapy in the future.

Advances in Pemphigus Therapy

The pemphigus variants represent a group of potentially life-threatening autoimmune mucocutaneous blistering diseases. Herein, we focus on the new and emerging therapies in the management of pemphigus.

Update on Drugs and Drug News – July-August 2006

Update on Zoster Vaccine Live Zostavax®, Doxycycline, 40mg Oracea®, Hyaluronic Acid Dermal Filler Juvéderm® Gel, Mycophenolate Mofetil CellCept®, Suberoylanilide Hydroxamic Acid (SAHA) Zolinza®, Quadrivalent Human Papillomavirus Recombinant Vaccine Gardasil®, and Adalimumab Humira®.

The A-B-C-Ds of Sensible Sun Protection

Ultraviolet (UV) radiation is a carcinogen that also compromises skin appearance and function. Since the UV action spectra for DNA damage, skin cancer, and vitamin D photosynthesis are identical, and vitamin D is readily available from oral supplements, why has sun protection become controversial?

Ciclopirox Nail Lacquer Topical Solution 8%

Ciclopirox nail lacquer 8% (Penlac, Aventis Pharma) was approved by the US FDA in December 1999, as a component of a comprehensive management program, for use in immunocompetent patients who have mild to moderate onychomycosis of the fingers and toes without lunula involvement due to Trichophyton rubrum.

Dermal Fillers: Ever-Expanding Options For Esthetic Use

Aesthetic volume rejuvenation with dermal fillers continues to be a popular procedure that is sought by a growing number of patients who seek the rounder softer contours attributable to a more youthful appearance. This article will focus on the most popular, time tested, and innovative fillers available today.

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