Drug Class | Generic/Trade/ Company Names | Indication | Approving Regulatory Agency |
HIV and AIDS | Abacavir Sulfate Ziagen Glaxo Wellcome | - A nucleoside analogue reverse transcriptase inhibitor for the treatment of HIV and AIDS
| HPB – Ottawa |
Male Pattern Hair Loss | Minoxidil 2% Topical Solution Taisho | | Japanese Pharmaceutical and Medical Safety Bureau |
Finasteride Propecia 1mg Tablets Merck Sharp & Dohme | - An additional indication of male-pattern hair loss
| UK MCA |
Oncologic Agents | Aldesleukin Proleukin Chiron | - An additional indication for treatment of malignant metastatic melanoma
| HPB – Ottawa |
Alitretinoin Panretin Gel 0.1% Ligand Pharmaceutical | - For topical treatment of cutaneous lesions in patients with AIDS related Kaposi’s Sarcoma
| US FDA HPB – Ottawa |
Allovectin-7 Vical | - For treatment of invasive and metastatic melanoma
| US FDA (orphan drug status) |
Bexarotene Targretin 75mg Capsules Ligand Pharmaceuticals | - For treatment of cutaneous manifestations of cutaneous T-cell lymphoma (CTCL) in patients who are refractory to one or more prior systemic treatments for CTCL
| US FDA |
Denileukin Diftitox Ontak Ligand Pharmaceuticals | - For the treatment of CTCL
| US FDA (accelerated approval) |
G-3139 Vical | - For the treatment of advanced malignant melanoma
| US FDA (fast-track designation) |
Interferon Alpha-2a Roferon-A Hoffmann-La Roche | - For the adjuvant treatment of malignant melanoma patients who are at risk for relapse following resection
| European Commission (CPMP) |
Melanoma Lysate Melacine Therapeutic Vaccine Schering-Plough | - For the treatment of late stage (IV) melanoma
| HPB – Ottawa |
Methoxsalen Uvadex Therakos | - For palliative treatment of the skin manifestations of CTCL that are unresponsive to other forms of therapy
| US FDA |
Osteoporosis | Alendronate Fosamax Merck | - For treatment of glucocorticoid induced osteoporosis in patients receiving glucocorticoids in a daily dosage equivalent to ≥ 7.5mg prednisone and who have low bone mineral density
| US FDA |
Pediculocides | Malathion Ovide 0.5% Lotion Medicis Pharmaceutical | - For treatment of head lice and their ova
| For treatment of head lice and their ova US FDA |
Pyrethrins/Piperonyl Butoxide Rid Aerosol Foam Mousse Pfizer | - For treatment of head lice
| US FDA |
Photodynamic Therapy | Aminolevulinic Acid Levulan Photodynamic Therapy DUSA Pharmaceuticals | - For treatment of actinic keratoses of the face and
scalp
| US FDA |
Topical Anesthetics | Lidocaine 5% Lidoderm Patch Endo Pharmaceuticals | - For treatment of postherpetic neuralgia
| US FDA |
Lidocaine/Prilocaine EMLA Cream Astra | - An additional indication for use in pediatric patients
| US FDA |
Vaginal Atrophy | Estradiol Estradiol Transdermal System Wyeth Ayerst Laboratories | - For the treatment of vulvar and vaginal atrophy
| US FDA |