UPDATE ON DRUGS
|Class||Name/Company||Approval Dates and Comments|
|The US FDA approved this monoclonal antibody in May 2005 for the treatment of psoriatic arthritis. This is the ninth new indication for this product.|
|TPP Canada issued a Health Advisory in May 2005 informing consumers of a new version of the product monograph agreed upon by Berlex and TPP Canada that includes the following information:|
Any occurrences of thromboembolic disorders (blood clots) or other serious and/or unexpected adverse reactions in patients taking Diane-35® should be reported to TPP Canada.
|Antipsoriatic Agent||Biogen Idec and Fumapharm AG in April 2005, announced results from a multicenter, double-blind, placebo-controlled Phase III study designed to evaluate the efficacy and safety of BG-12, an oral fumerate, in the treatment of moderate-to-severe psoriasis. The trial met the primary endpoint and|
patients receiving BG-12 demonstrated a statistically significant clinical improvement as measured by a lower median psoirasis severity score after 16 weeks of treatment compared with patients receiving placebo. The median PASI was 5.8 for the BG-12 group and 14.2 for the placebo group.
Median percentage reduction from baseline PASI was 68% for patients receiving BG-12 and 10% for patients receiving placebo.
|Hair Dye||In an article recently published in of the scientific evidence looking|
strong evidence of increased risk. hematopoietic cancers (e.g., leukemia of a causal effect is too weak to represent a major public health concern.*JAMA 293:2516-25 (2005).