Fungal Infections

Read articles about various fungal infections, and managing its symptoms as well as their treatments.

Unanswered Questions in Antifungal Therapy for Onychomycosis

Onychomycosis has a significant impact on the patient. With three new, orally effective, antifungal agents, we have for the first time effective treatment that can provide benefit for a high percentage of patients. This review examines some of the areas of uncertainty and controversy.

Fungal Treatment: Understand The Objective and Limitations of Therapy

A top down overview of the available treatments for fungal infections, as well as the limitations of these therapies.

Device-Based Therapies for Onychomycosis Treatment

Device-based therapies are promising alternatives for the treatment of onychomycosis because they can mitigate some of the negative factors associated with treatment failure. This article reviews the case for laser and light based therapies, for the treatment of nail fungus.

Tavaborole 5% Solution: A Novel Topical Treatment for Toenail Onychomycosis

Onychomycosis is a stubborn fungal infection of the nails that can be difficult to manage. Clinical trial data of Tavaborole is considered, as it allows for effective nail penetration compared to ciclopirox and amorolfine lacquers.

The Scoring Clinical Index for Onychomycosis (SCIO Index)

Onychomycosis is a common disease, and there are a number of factors that may affect the duration and dosage of treatment including the type of onychomycosis, the area and thickness of nail involvement, the age of the patient, and the location of the digit that is affected.

Overview of Treatment of Vulvovaginal Disease

Vulvovaginal diseases commonly are inadequately diagnosed and treated. This article discusses the important role dermatologists play in identifying irregular presentations, recognizing skin problems, and addressing itch, pain, and inflammation.

Itraconazole

Itraconazole is an antifungal azole, and its use, indication, potential contraindications, and adverse events and drug interactions are discussed in this article.

Update on Efinaconazole 10% Topical Solution for the Treatment of Onychomycosis

Update and discussion on onychomycosis (nail fungus) and Efinaconazole 10%. Recent clinical trial results, and discussion about patient safety profile, special cases like diabetic patients, and cure rates.

Terbinafine Hydrochloride

Terbinafide hydrochloride, its use, indication, potential contraindications, and adverse events and drug interactions are discussed in this article.

Ciclopirox

Ciclopirox olamine is a hydroxypyridone antifungal that is used to treat fungal infections. Indication, brand names, therapeutic regimen, and safety information are discussed.

Ciclopirox (Loprox®) Gel for Superficial Fungal Infections

Ciclopirox (Loprox®) is a broad-spectrum antifungal medication that also has antibacterial and anti-inflammatory properties. Ciclopirox is indicated in the US for the treatment of tinea pedis, tinea corporis, pityriasis versicolor, seborrheic dermatitis, and cutaneous candidiasis.

Efinaconazole: A New Topical Treatment for Onychomycosis

Nail fungus, left untreated, the infection can spread to other nails and potentially cause further complications. This article reviews efinaconazole 10% as a topical monotherapy. Clinical trial data, mechanism of action, and future treatments are discussed.

Management of Onychomycosis

Diagnosis of onychomycosis can only be established with a positive culture or observation of fungus in the nail clippings. Consideration should be given to cost and possible complications before starting treatment. Recurrent disease is a problem even after a complete cure.

Ciclopirox Nail Lacquer Topical Solution 8%

Ciclopirox nail lacquer 8% (Penlac, Aventis Pharma) was approved by the US FDA in December 1999, as a component of a comprehensive management program, for use in immunocompetent patients who have mild to moderate onychomycosis of the fingers and toes without lunula involvement due to Trichophyton rubrum.

A Simple Algorithm for the Treatment of Dermatophyte Toenail Onychomycosis

There has been much discussion about the optimal treatment for onychomycosis. We propose a simple algorithmic approach to aid in the selection of therapy for dermatophyte toenail onychomycosis and present a balance between efficacy and risk of therapy.

Efinaconazole in the Treatment of Onychomycosis: Managing Patient Expectations and Promoting Compliance

Onychomycosis, also known as tinea unguium, is a progressive fungal infection of the nails resulting in discoloration, nail plate thickening, and onycholysis. Efinaconazole 10% solution is an effective and convenient topical antifungal treatment for onychomycosis, with toenail mycological cure rates between 53.4% and 55.2% and complete cure rates between 15.2% and 17.8%.

Ketoconazole

Ketoconazole, its use, indication, potential contraindications, and adverse events and drug interactions are discussed in this article.

Treatments for Skin, Nail and Hair Infections

Fungal infections can affect the hair and nails as well as the skin. This article reviews the various conditions that can arise from fungal infections, and their treatments.

Ciclopirox Nail Lacquer 8% for the Treatment of Onychomycosis: A Canadian Perspective

Onychomycosis is prevalent, and risk factors, such as old age and diabetes, are increasing. This condition has been treated using oral antifungal agents with varying degrees of success. Recently, ciclopirox nail lacquer 8% solution became the first topical agent approved in Canada for onychomycosis.

Topical Efinaconazole in the Management of Toenail Onychomycosis

Onychomycosis is a fungal infection of the nail caused by dermatophytes, yeasts, or non-dermatophyte molds. Here we discuss using topical Efinaconazole in the management of toenail onychomycosis.

Onychomycosis: Therapy Directed by Morphology and Mycology

Onychomycosis is one of the most common nail disorders. Despite recent therapeutic advances with the introduction of effective systemic agents and transungual drug delivery systems, the incidence of onychomycosis is increasing.

Fluconazole

Fluconazole is an antifungal azole, and its use, indication, potential contraindications, and adverse events and drug interactions are discussed in this article.

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