Psoriasis

Read articles about psoriasis and its management, as well as its treatment options.

New Systemic Treatments for Psoriasis

Biologics are one of the more effective and relatively safe options for long-term control of psoriasis. They have reduced the time needed to clear the signs of chronic disease, and are effective in maintaining a disease-free state for longer durations. Biologics can safely be used with other treatment modalities (i.e., methotrexate, cyclosporine, acitretin and hydroxyurea).

Psoriasis Treatments Under Development

A review of this list of agents that are presently undergoing clinical trial. Although only a few of the drugs on this list will gain regulatory approval, what is exciting is the likelihood that some new agents will be approved and will radically alter the way we treat psoriasis.

A Review of Corticosteroids for the Treatment of Psoriasis

A review of corticosteroids, including use, adverse effects, vehicle, generic vs brand name drugs. Physicians and pharmacists alike should be aware of the importance and the difference of various vehicles when prescribing topical corticosteroids.

Oral Treatment for Psoriasis

Oral treatments for treating psoriasis are discussed. This article focuses on methotrexate, acetretin, and cyclosporine.

Efalizumab (RAPTIVA®)

This article provides an overview for the drug, Efalizumab (RAPTIVA®) for the treatment of psoriasis. Indications, mechanism, contraindications, side-effects are considered.

Alefacept (Amevive) IM administration

In October 2004 Amevive® (alefacept) became the first biologic approved for psoriasis in Canada. It is used to treat moderate to severe psoriasis. This article discusses clinical trials, side effects, and drug interactions.

Etanercept (Enbrel)

Etanercept is a TNF-alpha receptor fused onto human IgG and inhibits TNF-alpha activity. Dosage, side-effects, and drug interactions are discussed.

Topical Therapy of Psoriasis Vulgaris

Psoriasis, its diagnostic features, and impact on the patient's quality of life are discussed as well as the most common topical treatments for psoriasis.

Infliximab (Remicade)

Infliximab is monoclonal antibody targeted against human tumor necrosis factor-alpha. Dosage, side-effects, and drug interactions are discussed.

Scalp Psoriasis

Various treatment modalities for the treatment of scalp psoriasis are considered, as well as their upsides and downsides. A list of practical tips in management are also provided.

Fixed Combination Halobetasol Propionate and Tazarotene Lotion for Plaque Psoriasis

A novel fixed combination lotion containing the super-potent corticosteroid halobetasol propionate 0.01% and retinoid tazarotene 0.045% (Duobrii™) has recently been introduced and indicated for the treatment of moderate to severe plaque psoriasis in adults.

Psoriasis Education Tool for Patient-Physician Decision-Making About Biologics: A Pilot Study

Although biologics are well-studied, expertise regarding their use is often lacking. Many biologics have been added to the market in recent years with distinctive characteristics. This study was designed to create a tool to assist physicians involved in the care of patients with psoriasis undergoing biologic treatment.

How to Use Halobetasol Propionate and Tazarotene Lotion to Treat Psoriasis

A fixed combination halobetasol propionate and tazarotene lotion (HP/TAZ) was launched in Canada in 2020, to treat moderate to severe plaque psoriasis in adults. With the use of polymeric emulsion technology, there is uniform distribution of HP and TAZ and excipients on the skin and improved skin moisturization.

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